+45 5192 2430

 

Pharmacokinetics

We conduct pharmacokinetic (PK) studies in mice, rats, rabbits, minipigs and conventional pigs with laboratories, protocols and processes designed specifically to meet the requirements of pharmacokinetics.

Our experienced study directors will help you set up the pharmacokinetic, pharmacodynamic, or biodistribution studies suitable for your unique research needs. Studies are always customized to the special requirements of our clients. From standard screening to more complex studies we will assist in designing the best strategy and protocols. We have experience with small chemical compounds, peptides, proteins, antibodies, nanoparticles and even implants and sustained release depots. Study times range from short term single dose studies of a few hours to long term repeated dose or depot formulation of six months.

We conduct pharmacokinetic (PK) studies in mice, rats, rabbits, minipigs and conventional pigs with laboratories, protocols and processes designed specifically to meet the requirements of pharmacokinetics.
Well-designed PK studies using appropriate administration routes provide data to assist in the study design and species selection for efficacy and proof of concept studies

Well-designed PK studies using appropriate administration routes provide data to assist in the study design and species selection for efficacy and proof of concept studies, including dosing schedule and dose levels. At Timeline we are capable of dosing test-articles using various administration routes in both rodents and large animals.

We focus on executing in-life phase services which is our core competence. Many of our customers prefer to perform bioanalysis at their own bioanalytical laboratories. For customers that do not have their own bioanalytical laboratories, we offer professional bioanalytical services at selected CRO’s that focus on this discipline. 

Drug discovery is often an iterative process, with selection of new compounds with desirable pharmacokinetic profiles for further investigation. Pharmacokinetic screening studies that includes fast start-up and quick turnaround time are therefore essential for efficient lead optimization or evaluation of different formulations. Additionally, for selected test-articles it can also be of importance to test the compounds in mice or/and rats as well as in larger animals such as pigs. Hence, at Timeline Bioresearch we are able conduct pharmacokinetic studies in rodents as well as large animals.